Product ID:DEPAKENE VALPROIC ACID CAPSULES AND SYRUP, 5681, 5682
MSDS Date:07/20/1987
FSC:6505
NIIN:01-094-9241
MSDS Number: BWLFT

Emergency Phone: 312-937-6100

Info Phone: 312-937-7350

Preparer: JIM MOOMEY

Cage: 70048

Telephone: 847-935-7155

Cage: 70048

VALPROIC ACID

CAS: 99-66-1

RTECS: YV7875000

Fraction By Weight: 54%

LD50 LC50 Mixture:LD50 ORAL, RATS/MICE=670-2307 MG/KG.
Routes of Entry: Inhalation:NO Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:VALPROIC ACID CAN CAUSE MODERATE SKIN
IRRITATION AND SEVERE CONJUNCTIVAL IRRITATION. ANIMAL STUDIES HAVE
REPORTED REPRODUCTIVE & TERATEGENIC EFFECTS.
Explanation of Carcinogenicity:PER
MSDS:CARCINOGENICITY:NTP/IARC/OSHA:NO.
Effects of Overexposure:NONE EXPECTED FOR OCCUPATIONAL EXPOSURE. REFER
TO PHYSICIANS DESK REFERENCE (PDR) FOR CLINICAL SYMPTOMS.
Medical Cond Aggravated by Exposure:NONE KNOWN FOR OCCUPATIONAL
EXPOUSRE. REFER TO THE PDR FOR CLINICAL INFORMATION.

First Aid:REMOVE FROM SOURCES OF EXPOSURE. IF SKIN OR EYE CONTACT,
FLUSH WITH COPIOUS AMOUNTS OF WATER. IF IRRITATION DEVELOPS OR
SYMPTOMS OF TOXICITY OCCUR SEEK MEDICAL ATTENTION.

Extinguishing Media:USE MEDIA APPROPRIATE FOR PRIMARY CAUSE OF FIRE.
Fire Fighting Procedures:NONE KNOWN.
Unusual Fire/Explosion Hazard:NONE KNOWN.

Spill Release Procedures:NO SPECIAL PROCEDURES REQUIRED.

Handling and Storage Precautions:NONE REQUIRED UNDER NORMAL USE.
Other Precautions:NONE REQUIRED UNDER NORMAL USE.

Work Hygienic Practices:USE GOOD CLINICAL AND HYGIENIC PRACTICES.
Supplemental Safety and Health

HCC:N1
Solubility in Water:SOLUBLE
Appearance and Odor:ORANGE COLORED SOFT GELATIN CAPSULES OR RED SYRUP.

Stability Indicator/Materials to Avoid:YES
NONE UNDER NORMAL USE.
Stability Condition to Avoid:NONE UNDER NORMAL USE.
Hazardous Decomposition Products:OXIDES OF NITROGEN.

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE AND
FEDERAL REGULATIONS.

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This information is formulated for use by elements of the Department
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document should seek competent professional advice to verify and
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particular situation.